WebOverall, by addressing the interaction of TLR1/2, TLR4, TLR7 and TLR9 in the induction of CSR and modulation of TLR-dependent CSR by BCR and CD40, our study suggests the complexity of how different stimuli cross-regulate an important B cell differentiation process and an important role of TLRs in inducing effective T-independent antibody ... WebSep 1992 - Nov 200210 years 3 months. Jim helped guide the growth of this upscale national restaurant chain from a single unit to twenty-four at the time he left. As a …
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